Sunday, October 19, 2014

A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS

A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS

Solicitation Number: PHS-2015-1
Agency: Department of Health and Human Services
Office: National Institutes of Health
Location: National Institute of Allergy and Infectious Diseases
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PHS-2015-1
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Solicitation
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Added: Jul 31, 2014 2:29 pm
1. National Institutes of Health, Bethesda, MD 20892 and Centers for Disease Control and Prevention, Atlanta, GA 30305 are soliciting proposals from small business concerns that possess the research and development (R&D) expertise to conduct innovative research that will contribute toward meeting the program objectives of the agencies. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES (DHHS), THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) SMALL BUSINESS INNOVATIVE RESEARCH (SBIR) PROGRAM SOLICITATION PHS 2015-1 with a closing date on or about November 5, 2014, for receipt of proposals, soon will be available electronically through the NIH Small Business Research Funding Opportunities (http://sbir.nih.gov) Web site and at fedbizopps.gov. The SBIR Phase I, Fast-Track, Direct to Phase II Contract Solicitation will be available ONLY via electronic means. Printed copies of the Solicitation will not be distributed. Potential offerors are encouraged to check the NIH Small Business Research Funding Opportunities Web site and fedbizopps.gov for updates on the program. Any updates or corrections to the Solicitation will be posted there. The purposes of the SBIR program are to: (a) stimulate technological innovation in the private sector; (b) strengthen the role of small business in meeting Federal research/research & development (R/R&D) needs; (c) increase the commercial application of Federally-supported research results; (d) foster and encourage participation by socially and economically disadvantaged small business concerns and women-owned business concerns; and improve the return on investment from Federally-funded research for economic and social benefits to the Nation. For purposes of the SBIR program, a small business concern is any business concern that, on the date of award, (1) is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor; (2) is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture; (3) more than 50% directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50% directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these; OR more than 50% owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50% of the concern AND (4) has, including its affiliates, no more than 500 employees. Following are the research topics identified in the NIH/CDC SBIR Contract Solicitation [PHS 2015-1]: NATIONAL INSTITUTES OF HEALTH (NIH) - NATIONAL CANCER INSTITUTE (NCI): Vacutubes to Preserve the Viability of Circulating Tumor Cells; Development of Advanced Culture Systems for Expansion of Cancer Stem Cells; Development of Novel Therapeutic Agents That Target Cancer Stem Cells; Cell-Free Nucleic Acid-Based Assay Development for Cancer Diagnosis; Predictive Biomarkers of Adverse Reactions to Radiation Treatment; Systemic Targeted Radionuclide Therapy For Cancer Treatment; Validation of Mobile Technologies for Clinical Assessment, Monitoring, and Intervention. NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES (NCATS): Exploring the Potential of CRISPR/CAS Genome-editing Tools; Assay Development for High-Throughput Screening of Chemicals of Toxicological Concern; Simple and Robust Reaction Progress Analyzer; Online Real Time Metals Analysis at Low ppm Level. NATIONAL HEART, LUNG AND BLOOD INSTITUTE (NHLBI): Transcatheter Cerclage Mitral Annuloplasty (SBIR-TT); Closure Devices for Transcaval Access to the Abdominal Aorta; In-bore Defibrillation for Invasive MRI Cardiology Procedures; Devices to Close Ductus Arteriosus in Premature Infants; Therapeutic Delivery of ADP-ribosylarginine Hydrolase; Selective Silencing of Stat3 Signaling to Treat Relapsed Disease After Transplantation; Cellular Immunotherapy After Stem Cell Transplantation. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID): Development of Novel Influenza Antivirals; Methods of Clinical Sample Preparation for Rapid Detection of Bacterial Pathogens; Inhaled Delivery of Clofazimine (CFZ) - An Important Anti-tuberculosis Drug; Simple, Inexpensive Unit for Removing Cells from Small Amounts of Blood in Resource-Limited Settings. NATIONAL INSTITUTE ON DRUG ABUSE (NIDA): Mobile Technologies Extending Reach of Primary Care for Substance-Use-Disorders. CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) - CENTER FOR GLOBAL HEALTH (GCH): Diagnostic Tools to Support the Elimination and Control of Neglected Tropical Diseases. NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION (NCCDPHP): Optical Character Recognition Software for Scanning Nutrition Facts Panel. NATIONAL CENTER FOR EMERGING ZOONOTIC AND INFECTIOUS DISEASES (NCEZID): Development of Nanoparticle Dengue Diagnostic Tests. NATIONAL CENTER FOR HIV/AIDs, VIRAL HEPATITIS, STD, AND TB PREVENTION (NCHHSTP): Yeast-derived Candidate of Hepatitis E Virus Vaccine; Multiplex Assay for Simultaneous Detection of Hepatitis and Other Viruses; Improved Antibody Preparation for Post-Exposure Prophylaxis Against Hepatitis A. NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES (NCIRD): Thermostable Dry Vaccine Formulation for Microneedle Administration; Thermostable Oral Vaccines to Combat Enteric Diseases.


2. NIH/CDC SBIR Contract Solicitation PHS 2015-1, including proposal forms, will be available electronically on/around August 15, 2014 through the NIH Small Business Research Funding Opportunities Web site and at fedbizopps.gov. (Note: The PHS 2014-2 Omnibus Solicitation of the National Institutes of Health, Centers for Disease Control and Prevention, Food and Drug Administration, and Administration for Children and Families for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) GRANT Applications, where investigator-initiated ideas are encouraged, is still open and is available at the same Web site noted above with a remaining due date of December 5, 2014.) To understand better the differences between grants and contracts, see Contracts vs. Grants: What's the difference? (http://grants.nih.gov/grants/funding/contracts_vs_grants.htm) LINKURL: http://grants.nih.gov/grants/funding/sbir.htm LINKDESC: National Institutes of Health Small Business (SBIR/STTR) Research Funding Opportunities. E-mail: sbir@od.nih.gov
Added: Aug 15, 2014 2:56 pm

Points of Contact:

Office of Extramural Programs, Office of Extramural Research, National
Institutes of Health, Phone 301-435-2688, sbir@od.nih.gov.

Contracting Office Address:

Office of Acquisitions
5601 Fishers Lane, Suite 300, MSC 9821
Bethesda, Maryland 20892-9821

Primary Point of Contact:

Office of Extramural Programs, Office of Extramural Research,
National Institutes of Healthsbir@od.nih.gov
Phone: 301-435-2688
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Solicitation 1

Type:
Solicitation
Posted Date:
August 15, 2014
PHS2015-1.pdf (944.13 Kb)
Description: U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES (HHS), THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) SMALL BUSINESS INNOVATIVE RESEARCH (SBIR) PROGRAM

PROGRAM SOLICITATION PHS 2015-1

Amendment 1

Type:
Mod/Amendment
Posted Date:
September 11, 2014
Description: PHS 2015-1, Amendment 1 - The purpose of this amendment is to provide corrections and revisions to Sections 3.1, 3.2, 6.4, 8.3, 9, 10, and 12 of the subject solicitation.
Description: Attachment: PHS 2015-1 - Amendment One

Amendment 2

Type:
Mod/Amendment
Posted Date:
October 17, 2014
Amendment_No._2.pdf (160.82 Kb)
Description: The purpose of this amendment is to provide revisions to Section 12 of the subject solicitation and to respond to questions.
:
Office of Acquisitions
6700 B Rockledge Room 3214 MSC7612
Bethesda, Maryland 20892-7612
:
Tiffany Chadwick,
Contract Specialist
Phone: 301-435-0699
:
George Kennedy,
Contracting Officer
Phone: 301-451-2607

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